Evidence Library
Every claim grounded in published research. 18 studies spanning multiple treatment areas, two systematic reviews, and measurable outcomes verified by ultrasound biometrics — not estimated, not projected.
Published Studies
Systematic Reviews
Researchers
With DOI Links
One-page PDF with all 18 studies — formatted for physician handouts
18 studies
Landmark Studies
Studies with the olive accent border represent foundational evidence — the largest datasets, histological proof, multi-year clinical experience, and systematic reviews that anchor Junera's clinical positioning.
Reynaud JP, Skibinski M, Wassmer B, Rochon P, Mordon S
Aesthetic Plastic Surgery, 2009 — 334 patients, 534 procedures
Key finding: 80% patient satisfaction rate across all treated areas
Bollero D, Orlando G, Dell'Avanzato R, Cambieri I, Bovani B, Minzon S, Forte R, Senetta R, Scutera S, Musso T
Aesthetic Plastic Surgery, 2014 — Histological biopsy study
Key finding: 20 J/cm² established as optimal energy density for neocollagenesis
Nilforoushzadeh MA, Heidari-Kharaji M, Najar Nobari N, Torkamaniha E, Rafiee S, Shahverdi M, Tehrani S, Fakhim T
Skin Research and Technology, 2024 — Clinical case series
Key finding: 48.75% increase in dermis density measured by ultrasound
Nilforoushzadeh MA, Heidari-Kharaji M, Fakhim T, Hosseini ST, Rafiee S, Shahverdi M, Najar Nobari N
Skin Research and Technology, 2023 — 10 female subjects
Key finding: 43.75% increase in dermis density
Nilforoushzadeh MA, Heidari-Kharaji M, Najar Nobari N, Torkamaniha E, Rafiee S, Shahverdi M, Fakhim T
Journal of Cosmetic Dermatology, 2022 — Clinical case series
Key finding: 90% of patients showed excellent improvement
Nilforoushzadeh MA, Heidari-Kharaji M, Fakhim T, Najar Nobari N, Rafiee S, Shahverdi M
Dermatologic Surgery, 2022 — Clinical case series
Key finding: ~90% patient and physician satisfaction
Nilforoushzadeh MA, Heidari-Kharaji M, Fakhim T, Najar Nobari N, Rafiee S, Shahverdi M
Journal of Cosmetic Dermatology, 2023 — Clinical case series
Key finding: Effective non-surgical treatment for upper eyelid and eyebrow ptosis
Nilforoushzadeh MA, Heidari-Kharaji M, Fakhim T, Najar Nobari N, Rafiee S, Shahverdi M
Journal of Cosmetic Dermatology, 2023 — 10 patients
Key finding: Significant fat and circumference reduction in arms and under abdomen
Suárez MG, Sanabria B, González A
Clinical Dermatology Research, 2022 — Clinical case series
Key finding: Significant dermis thickness and density increase at 90 days
de Moura AO, Borges FS, de Moura AC
International Journal of Medical Science and Clinical Invention, 2023 — 4-year clinical experience
Key finding: Confirmed body contouring efficacy across multiple treatment areas
de Moura AC, Borges FS, de Moura AO
International Journal of Medical Science and Clinical Invention, 2023 — 4 cases
Key finding: Dual-wavelength approach effective for large abdomen treatment
de Moura AO, Borges FS, de Moura AC
Clinical case report, 2023 — Case report
Key finding: 980nm vascular targeting combined with 1470nm tissue remodeling
Nilforoushzadeh MA, Heidari-Kharaji M, Fakhim T, Najar Nobari N
Skin Research and Technology, 2024 — Clinical case series
Key finding: Combination of subdermal laser with nanofat grafting effective for neck lines
Nilforoushzadeh MA, Heidari A, Ghane Y, et al.
Aesthetic Plastic Surgery, 2024 — Systematic review of multiple studies
Key finding: Comprehensive systematic review confirming efficacy across multiple indications
Elicit Research (AI-assisted systematic review)
Elicit Research Report, 2024 — 31 studies (499 papers screened)
Key finding: Systematic review of 31 studies from 499 papers screened
Elicit Research (AI-assisted systematic review)
Elicit Research Report, 2024 — Multi-study review
Key finding: Detailed mechanistic analysis of collagen denaturation and neocollagenesis
Borges FS, Jahara RS, Meyer PF, de Almeida ACT, et al.
World Journal of Biology Pharmacy and Health Sciences, 2023 — Case series + literature review
Key finding: Documents complications from improper technique — reinforces training importance
Disclaimer: The clinical studies referenced on this page represent published peer-reviewed research and systematic reviews. Patient satisfaction rates are reported from published case series and may not be representative of all patient outcomes. Individual results may vary. Junera is FDA 510(k) cleared (K212734) as a powered laser surgical instrument. The studies listed here describe clinical applications investigated by independent researchers. Practitioners should exercise independent clinical judgment when determining treatment protocols.